SEDEX 86LT: The New Standard in LT‑ELSD for Analytical LC
The SEDEX 86LT is the next‑generation replacement for the SEDEX 85LT, delivering significantly enhanced sensitivity, dramatically reduced baseline noise, and improved analytical performance across HPLC, UHPLC and SFC workflows.
Fully aligned with validated LT‑ELSD methods, it offers a seamless upgrade path for existing users while providing a robust, modern platform for new laboratories.
Designed with total remote control, the SEDEX 86LT brings advanced low‑temperature ELSD capability to analytical environments seeking reliability, automation and superior reproducibility.
Enhanced Optics, New Nebulizers & Next‑Generation Evaporation
The SEDEX 86LT integrates multiple innovations to improve sensitivity and reduce noise:
- New nebulizers generation optimized for stability and reproducibility
- New evaporative unit with improved thermal efficiency
- Photodetector technology identical to the SEDEX 81LT and SEDEX 100LT
→ This results in very low baseline noise (~0.05 mV), compared to ~1 mV for the SEDEX 85LT. - Massively increased dynamic range, making it suitable for trace‑level detection as well as larger preparative peaks.
These enhancements ensure cleaner baselines, sharper peak shapes and higher signal‑to‑noise performance, even under challenging solvent conditions.
Full SAGA Integration: Automated Gain Management
The SEDEX 86LT features SAGA (SEDEX Automated Gain Adjustment), the same intelligent gain‑control technology found in higher‑end SEDEX models. SAGA automatically optimizes gain settings in real time to:
- prevent off‑scale peaks,
- ensure consistent sensitivity,
- expand usable dynamic range,
- simplify daily operation.
This automation eliminates manual gain selection — improving reproducibility and protecting data quality.
Enhanced Optics, New Nebulizers & Next‑Generation Evaporation
Designed to integrate easily into modern LC systems, the SEDEX 86LT offers:
- Total remote control (gas, light source, photodiode, temperature)
- Automatic end‑of‑run shutdown to save gas and extend instrument lifetime
- Compatibility with validated SEDEX 85LT method temperatures
- Effortless interchangeability for users upgrading from older SEDEX instruments
These features reduce running costs and ensure long‑term operational stability.
Key Benefits of the SEDEX 86LT
→ Dramatically Lower Baseline Noise
~0.05 mV vs ~1 mV on the SEDEX 85LT → cleaner chromatograms and easier quantification.
→ Full Remote Control for Automated Workflows
Ideal for regulated laboratories and fully instrumented LC systems.
→ SAGA Automatic Gain Adjustment
Protects the detector, expands dynamic range and simplifies method development.
→ Improved Nebulizer & Drift Tube Design
New generation of nebulizers and modern evaporation system ensure stability and robustness.
→ Seamless Replacement for SEDEX 85LT
Identical method temperatures, modernized hardware, lower noise, better sensitivity.
→ Universal Low‑Temperature Detection
Suitable for HPLC, UHPLC & SFC — detects virtually all compounds less volatile than the mobile phase.
Ideal Applications
- Routine HPLC with improved stability vs SEDEX 85LT
- UHPLC workflows requiring enhanced sensitivity
- SFC methods needing low‑noise aerosol detection
- QC labs upgrading from legacy ELSD technology
- Trace‑level quantification and high‑dynamic‑range analyses